The GEF way to MYD88-dependent vascular permeabilization
نویسندگان
چکیده
منابع مشابه
MyD88-dependent induction of allergic Th2 responses to intranasal antigen.
MyD88 is a common Toll-like receptor (TLR) adaptor molecule found to be essential for induction of adaptive Th1 immunity. Conversely, innate control of adaptive Th2 immunity has been shown to occur in a MyD88-independent manner. In this study, we show that MyD88 is an essential innate component in the induction of TLR4-dependent Th2 responses to intranasal antigen; thus we demonstrate what we b...
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ژورنال
عنوان ژورنال: Nature Reviews Immunology
سال: 2012
ISSN: 1474-1733,1474-1741
DOI: 10.1038/nri3354